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leprae. Anin silicostudy was carried out to understand the molecular interactions in between DNA gyrase and WQ compounds. WQ-3334 and WQ-3810 were revealed to own increased inhibitory exercise againstM. lepraeDNA gyrase than Many others. On top of that, Examination making use of quinolone-resistantM. lepraeDNA gyrases confirmed that WQ-3334 had inc